Best Biotechnology Stocks
Drug developers, gene therapy, mRNA platforms, diagnostics. Binary outcomes - patent + FDA risk dominate. Average ROIC negative because most pre-revenue names burn cash; the few winners compound aggressively.
Industry leader
Halozyme Therapeutics, Inc. HALO
Buffett-Fit: 69/100
What drives this industry
Biotechnology is the highest-variance industry in healthcare. Patent expirations are scheduled value destruction; FDA approvals are binary risk. The Buffett-Fit framework favours commercial-stage biotechs with sustained positive net income + clear pipeline depth - typically large-cap names rather than pre-revenue clinical-stage companies. Avoid the average; chase the winners.
Top 50 ranked by Buffett-Fit
Sorted by composite quality score - ROIC, margin stability, balance-sheet strength, growth quality. Click any ticker for the full Buffett verdict.
- 1
HALOHalozyme Therapeutics, Inc.8.1B mcap
69Q - 2
HRMYHarmony Biosciences Holdings, Inc.1.7B mcap
67Q - 3
RPRXRoyalty Pharma plc23.4B mcap
66Q - 4
NVONovo Nordisk A/S199.8B mcap
65Q - 5
GMABGenmab A/S16.5B mcap
65Q - 6
CRMDCorMedix Inc.626M mcap
63Q - 7
INCYIncyte Corporation19.4B mcap
63Q - 8
CORTCorcept Therapeutics Incorporated6.5B mcap
62Q - 9
UTHRUnited Therapeutics Corporation24.1B mcap
61Q - 10
ARGXargenx SE49.9B mcap
60Q - 11
CPRXCatalyst Pharmaceuticals, Inc.3.8B mcap
59Q - 12
ALNYAlnylam Pharmaceuticals, Inc.39.7B mcap
58Q - 13
ALKSAlkermes plc6.1B mcap
57Q - 14
PTCTPTC Therapeutics, Inc.5.7B mcap
57Q - 15
SLNOSoleno Therapeutics, Inc.2.8B mcap
57Q - 16
AUPHAurinia Pharmaceuticals Inc.2.0B mcap
56Q - 17
AKTSAktis Oncology, Inc.1.1B mcap
55Q - 18
TECHBio-Techne Corporation7.5B mcap
55Q - 19
BMRNBioMarin Pharmaceutical Inc.10.5B mcap
54Q - 20
VRTXVertex Pharmaceuticals Incorporated110.3B mcap
54Q - 21
EXELExelixis, Inc.12.6B mcap
54Q - 22
REGNRegeneron Pharmaceuticals, Inc.65.8B mcap
54Q - 23
TBPHTheravance Biopharma, Inc.844M mcap
53Q - 24
VCELVericel Corporation1.8B mcap
52Q - 25
VCYTVeracyte, Inc.3.6B mcap
50Q - 26
MDXGMiMedx Group, Inc.539M mcap
49Q - 27
ABUSArbutus Biopharma Corporation859M mcap
49Q - 28
TGTXTG Therapeutics, Inc.6.0B mcap
49Q - 29
XERSXeris Biopharma Holdings, Inc.1.1B mcap
49Q - 30
APLSApellis Pharmaceuticals, Inc.5.3B mcap
47Q - 31
LGNDLigand Pharmaceuticals Incorporated4.6B mcap
47Q - 32
LKFTGalapagos N.V. Sponsored ADR1.8B mcap
46Q - 33
INVAInnoviva, Inc.1.7B mcap
45Q - 34
JAZZJazz Pharmaceuticals plc15.0B mcap
44Q - 35
GYREGyre Therapeutics, Inc.588M mcap
44Q - 36
BTXBlackRock Technology and Private Equity Term Trust1.0B mcap
44Q - 37
TECXTectonic Therapeutic, Inc.549M mcap
43Q - 38
KRYSKrystal Biotech, Inc.8.8B mcap
43Q - 39
MNKDMannKind Corporation1.0B mcap
43Q - 40
BIOABioAge Labs, Inc.625M mcap
42Q - 41
LBRXLB Pharmaceuticals Inc Common Stock806M mcap
42Q - 42
FOLDAmicus Therapeutics, Inc.4.5B mcap
42Q - 43
TSHATaysha Gene Therapies, Inc.1.4B mcap
41Q - 44
GLPGGalapagos N.V.1.8B mcap
41Q - 45
ADMAADMA Biologics, Inc.1.9B mcap
41Q - 46
SRPTSarepta Therapeutics, Inc.1.8B mcap
40Q - 47
RIGLRigel Pharmaceuticals, Inc.537M mcap
40Q - 48
BCRXBioCryst Pharmaceuticals, Inc.1.7B mcap
40Q - 49
KNSAKiniksa Pharmaceuticals, Ltd.4.0B mcap
39Q - 50
XOMAXOMA Royalty Corp.522M mcap
38Q
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Key terms in this analysis
Educational framework analysis only. Not investment advice, not a recommendation, not personalized to your situation. Always do your own research.